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More problems , Global Alignment

Recall that in biological experiments only relatively short segments of the DNA can be investigated. To investigate the structure of a long DNA molecule, the DNA is broken into smaller fragments that can be studied more easily by biological experiments. For instance, physical mapping aims at ordering these fragments based on overlap information obtained from hybridization experiments with a set...

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1 Department of Computer Science, University of Illinois, 1304 West Spring eld Avenue, Urbana, IL 61801, U.S.A, [email protected] 2 Laboratoire de Recherche en Informatique, Bat. 490, Universit e de Paris Sud, 91405 Orsay, France, [email protected] 3 CWI, Kruislaan 413, 1098 SJ Amsterdam, The Netherlands Department of Mathematics and Computer Science, Free University, de Boelelaan 1081, 1081...

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Social Neuroscience: More Friends, More Problems…More Gray Matter?

The social brain hypothesis generically posits that increasing social group size relates is associated with an increase in neocortex size. A new study identifies, within a species, the specific neural circuit that may confer the primate ability to manage social relationships as they increase in number.

Accuracy of coalescent likelihood estimates: do we need more sites, more sequences, or more loci?

A computer simulation study has been made of the accuracy of estimates of Theta = 4Nemu from a sample from a single isolated population of finite size. The accuracies turn out to be well predicted by a formula developed by Fu and Li, who used optimistic assumptions. Their formulas are restated in terms of accuracy, defined here as the reciprocal of the squared coefficient of variation. This sho...